PK/PD – Pharmacokinetic and Pharmacodynamic

Pharmacokinetics is that branch of science, which deals with the time course of drug in the body. Specifically it is the study of drug absorption, distribution and elimination. The companion subject of pharmacodynamics deals with the time course of drug action and is intimately linked to pharmacokinetics.

Uses over 100 real-life Case Studies


Teaches Pharmacokinetic and Pharmacodynamic concepts to undergraduate and graduate scientists


Meets the requirements for courses in Quantitative Pharmacology (Pharmacometrics)


Encourages students to apply the methods outside of the classroom


Requires very little calculus or statistical methods

Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications teaches everyday biological data analysis to the undergraduate and graduate levels. Through numerous examples and over 100 tutorials, scientists learn how to use PKPD seamlessly in a variety of practical areas, from simple plasma kinetics, multi-compartment models, nonlinear kinetics, plasma protein binding, pharmacodynamic models, turnover concepts, receptor binding, functional adaptation and rebound, dose-response-time data analysis, inter-species scaling, target mediated drug disposition, and a lot more.

The text develops a logical, real-world approach to data and reasoning, showing the reader how to:

  • Think both analytically and visually about data
  • Use graphics to make a point
  • Improve your pattern recognition ability
  • Make sound decisions
  • Strategize your data analyses
  • Appreciate more fully the exciting field of Quantitative Pharmacology

Johan Gabrielsson, PhD

Author of both PK/PD books

He is professor of integrative Pharmacology at the SLU, Uppsala, Sweden. He has conducted numerous workshops (6000 participants) on biological PK/PD data analysis.
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Stephan Hjort, PhD

Author of Introduction to PK/PD Methods

Stephan Hjorth is Professor of Pharmacology. His research expertise focuses on mechanisms of drug action, mainly within the CNS area. He is also an avid mentor/educator in basic and continued pharmacological training contexts, with extensive experience from leading and advising in multiple drug Dx/Dev projects.
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Dan Weiner, PhD

Co-author of PK/PD Data Analysis

He is a consultant and trainer on PK/PD modeling and an adjunct professor with two universities.  He was the original developer of WinNonlin.